The method of claim 16 further comprising applying therapy to said target tissue in at least one said other region shown by said functional image to be suspicious for cancer. The method of claim 1 further comprising correlating a location of at least one said detectable marker whose corresponding pathological analysis is positive for cancer, with a location of said target tissue shown by at least one said functional image to be suspicious for cancer, and prescribing therapy to said target tissue in at least one other region shown by said functional image to be suspicious for cancer. The method of claim 14 wherein said applied therapy is selected from IMRT, EBRT, Cryotherapy, LDR, HDR, Hyperthermia, Photo Dynamic Therapy, HIFU and Gene Therapy. The method of claim 13 further comprising applying therapy to said target tissue in at least one region shown by said functional image to be suspicious for cancer. The method of claim 12, further comprising prescribing therapy to said target tissue based on said correlation, or prescribing one or more additional biopsies to said target tissue at locations other than said location of said detectable marker. The method of claim 1 comprising correlating said pathological analysis of said target tissue corresponding to said location of said at least one detectable marker with a diagnosis of said target tissue produced by said functional image at said location of said at least one detectable marker. The method of claim 10 wherein said markers are visually distinguishable based on their size shape, image intensity acoustical impedance, digital marker transmission or wavelength. The method of claim 1 comprising obtaining biopsy specimens and placing said detectable markers substantially at multiple said biopsy locations, and wherein a plurality of said markers are visually distinguishable from each other by at least one said anatomic image, functional image or a combination or hybrid thereof. The method of claim 1 wherein said target tissue is a prostate. The method of claim 7 wherein said separately acquired images are co-registered or fused using image fusion software. The method of claim 1 wherein said anatomic and functional images are acquired separately. The method of claim 5 wherein said hybrid or combination image is selected from SPECT/CT, PET/CT, SPECT/MR, PET/MR, SPECT/CT, SPECT/MR/US, SPECT/CT US, SPECT/CT/MRSI/US, SPECT/X-ray, and PET/X-ray. The method of claim 4 wherein said images are acquired as a hybrid or combination image. The method of claim 1 wherein said anatomic and functional images are acquired substantially simultaneously.
The method of claim 1 wherein said functional image is selected from SPECT, PET, MRSI, Optical Biopsy or a combination or hybrid thereof. The method of claim 1 wherein said anatomic image is selected from CT, MR, Xray, US, Fluoroscopy or a combination or hybrid thereof. A method of correlating a functional image of a target tissue to a pathology of said target tissue comprising: , f) correlating the location of said at least one detectable marker with a corresponding location on said functional image, whereby said pathological analysis of said target tissue corresponding to said location of said at least one detectable marker can be correlated to a diagnosis of said target tissue produced by said functional image at said location of said at least one detectable marker. a) obtaining at least one biopsy specimen from said target tissue at a corresponding biopsy location ī) placing a detectable marker substantially at said biopsy location, and correlating said marker to said biopsy location Ĭ) obtaining a pathological analysis of said biopsy specimen and correlating said pathological analysis of said specimen to said biopsy location ĭ) obtaining at least one anatomic image of said target tissue which detects a location of at least one said detectable marker Į) obtaining at least one functional image of said target tissue and.
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